Work out pedigree risk instantly with clear inputs, formula shown and shareable results.
Applies the standard Mendelian recurrence risks for autosomal recessive, autosomal dominant and X-linked recessive patterns.
Recurrence risks
Autosomal recessive with two carriers: 25% affected, 50% carriers. Autosomal dominant with one affected parent: 50%. X-linked recessive with a carrier mother: 25% of all children, or 50% of sons
Educational estimate only. Not a substitute for professional clinical judgement, and must not be used to make treatment or dosing decisions.
Yes. Each conception is independent, so three unaffected children do not lower the risk for the fourth.
Dominant conditions with reduced penetrance carry a lower observed risk of disease than the 50% transmission risk.