Work out bioavailability instantly with clear inputs, formula shown and shareable results.
Compares dose-normalised exposure after oral and intravenous administration to give absolute bioavailability.
Absolute bioavailability
F = (AUC oral / dose oral) / (AUC IV / dose IV) x 100
Educational estimate only. Not a substitute for professional clinical judgement, and must not be used to make treatment or dosing decisions.
Incomplete absorption and first-pass metabolism in the gut wall and liver.
A comparison between two non-intravenous formulations, which is what bioequivalence studies measure.