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Chemotherapy Dose (Carboplatin) Calculator

Work out chemotherapy dose (carboplatin) instantly with clear inputs, formula shown and shareable results.

About Chemotherapy Dose (Carboplatin) Calculator

Applies the Calvert formula, which sets the carboplatin dose from the target area under the curve and renal function plus a fixed non-renal clearance of 25.

Formula

Calvert formula

Dose (mg) = target AUC (mg/mL/min) x (GFR mL/min + 25)

Worked example

With the default values below, Chemotherapy Dose (Carboplatin) Calculator returns Carboplatin dose of 525. Change any input above and every figure here is recalculated in your browser.

Inputs used

Target AUCaccepts 1–8 mg/mL/min
5 mg/mL/min
Glomerular filtration rateaccepts 10–200 mL/min
80 mL/min
Cap GFR at 125 mL/minone of Yes (common safety cap), No
Yes (common safety cap)

Results

Carboplatin dose
525 mg
GFR used after capping
80 mL/min
Dose per AUC unit
105 mg

Step by step

  1. 1Values used
  2. 2Calvert formula
  3. 3Carboplatin dose= 525 mg
  4. 4GFR used after capping= 80 mL/min
  5. 5Dose per AUC unit= 105 mg

Assumptions and limits

  • The result is derived only from the 3 inputs listed above. Anything not among them is not part of the calculation.
  • In particular, this calculator does not take inflation, tax, fees or charges or compounding frequency into account.
  • Figures are rounded for display to whole numbers, so totals built from several rounded parts can differ slightly from the unrounded arithmetic.
  • Educational estimate only. Not a substitute for professional clinical judgement, and must not be used to make treatment or dosing decisions.
  • This is an estimate for general information and not professional medical advice. See the full disclaimer for the limits that apply to this kind of calculator.

How these calculators are built and tested is described on the Methodology page. If a figure looks wrong, please report it.

Educational estimate only. Not a substitute for professional clinical judgement, and must not be used to make treatment or dosing decisions.

Frequently Asked Questions

Why cap the GFR?

Estimated GFR above 125 mL/min is unreliable and uncapped values can produce dangerous overdoses.

Which GFR should be used?

The Calvert formula was validated with isotopic GFR; creatinine-based estimates are substitutes and must follow local policy.

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