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Applies the start low and go slow principle by combining an age-based reduction with a renal function reduction on the standard adult dose.
Combined reduction
Adjusted dose = standard dose x age factor (0.75 from 75 years, 0.5 from 85) x renal factor (0.75 for CrCl 30-49, 0.5 below 30)
Educational estimate only. Not a substitute for professional clinical judgement, and must not be used to make treatment or dosing decisions.
Lean mass, renal clearance and hepatic blood flow all fall, while sensitivity to sedatives and anticholinergics rises.
No. Antibiotics and analgesics are often needed at full dose; the Beers and STOPP criteria identify the drugs that matter most.