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The uncertainty principle sets dx.dp >= hbar/2, so confining a particle sharpens its position at the cost of its momentum. Localising an electron to 0.1 nm - roughly an atom - forces a momentum spread of 5.3e-25 kg m/s, a speed uncertainty near 5.8e5 m/s. That confinement energy is why atoms have a definite size.
Heisenberg uncertainty principle
dx x dp >= hbar / 2
Confinement energy scale
E = dp^2 / (2m)
No - it is a property of the states themselves. A particle simply does not possess arbitrarily sharp position and momentum simultaneously.
Because hbar/2 is about 5e-35 J s. For a 1 kg object located to a micron the speed uncertainty is 5e-29 m/s, utterly negligible.